The typical recommended starting dosage for tadalafil is 10 mg, taken before anticipated sexual activity. The dosage may be adjusted based on individual response and tolerability. Tadalafil is usually taken as needed and not more than once in a 24-hour period.Tadalafil is a phosphodiesterase type 5 (PDE5) inhibitor, and it works by increasing blood flow to the penis, facilitating the ability to achieve and maintain an erection during sexual stimulation.