Vriligy 60 mg is primarily used to treat premature ejaculation (PE) in men. Dapoxetine, the active ingredient, is a selective serotonin reuptake inhibitor (SSRI) that works by increasing serotonin levels in the nervous system to help delay ejaculation. Dapoxetine works by inhibiting the serotonin transporter, increasing serotonin's action at the postsynaptic cleft, and promoting delay in ejaculation. It has a rapid onset of action and can be taken 1-3 hours before anticipated sexual activity.